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Persistent Symptoms in Patients After Acute COVID-19

In Italy, a large proportion of patients with coronavirus disease 2019 (COVID-19) presented with symptoms (71.4% of 31 845 confirmed cases as of June 3, 2020).1 Common symptoms include cough, fever, dyspnea, musculoskeletal symptoms (myalgia, joint pain, fatigue), gastrointestinal symptoms, and anosmia/dysgeusia.2-4 However, information is lacking on symptoms that persist after recovery. We assessed persistent symptoms in patients who were discharged from the hospital after recovery from COVID-19.

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Can angiotensin receptor-blocking drugs perhaps beharmful in the COVID-19 pandemic?

The novel coronavirus causing the COVID-19pandemic, SARS-CoV-2, gains entry to pulmonarycells after binding to membrane ACE2 [1]. Thisenzyme is a homologue of ACE1, which converts angiotensin I to angiotensin II, is active in cardiovascularcontrol, can be an element in cardiovascular disease,and is therapeutically targeted in hypertension andheart failure, using ACE1 inhibitors such as enalapriland lisinopril.

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